Research Papers (International and Local) authored by IBMBB staff and students 2004 to 2014

        2014
  1. Carvalho E, Punyasiri PAN, Somasiri HPPS, Abeysinghe ISB, Martens S, Quantification of γ-Aminobutyric Acid in Sri Lankan Tea by Means of Ultra Performance Tandem Mass Spectrometry. Natural Products Communications. 2014; 9(4).

  2.     2013

  3. Silva N, Tennekoon V, Wijayatunga N. What makes medical students to say “yes” to e-learning? Sri Lanka Journal of Bio-Medical Informatics.. 2013; 4(1):7-13.
  4. Kottawa-Arachchi JD, Gunasekare MTK, Ranatunga MAB, Punyasiri PAN, Jayasinghe L. What makes medical students to say “yes” to e-learning? J.Natn.Sci.Foundation Sri Lanka. 2013; 41 (4): 309-318.
  5. Rodrigo WWP, Dassanayake RS, Weerasena OVDSJ Genome orgamization and gene expression of a novel unannotated parasitic nematode-specific gene from Setaria digitata. Proceedings of the 69th Annual session of Sri Lanka Association for the Advancement of Science. 2013; p 13.
  6. Karunarathna KHT, Mewan KM, Punyasiri PAN, Brasathe J, Weerasena OVDSJ Variation of biochemical composition between blister blight resistant and susceptible tea (Camellia sinensis L.O. Kuntze) cultivars. Proceedings of the 69th Annual session of Sri Lanka Association for the Advancement of Science. 2013; p 165.
  7. Alahakoon S, Weerasena OVDSJ, Samarasekera R. Genome orgamization and gene expression of a novel unannotated parasitic nematode-specific gene from Setaria digitata. Proceedings of the 69th Annual session of Sri Lanka Association for the Advancement of Science. 2013; p 265.

  8.     2012

  9. Pradeepa NHL, Weerasena OVDSJ, Liyanarachchi CJ, Karunajeewa DGNP, Mahindapala KGJP, Wijesundera RLC, Abesinghe ISB. Sensitivity of Macrophoma theicola (Petch) Isolates Associated with tea in Sri Lanka to the Fungicide Hexaconazole. Proceeding of the Fourth Symposium on Plantation Crop Research. 155-161.
  10. Rajkumar G, Weerasena OVDSJ, Fernando KKS, Ratnasiri PW. Morphological and Molecular comparison of O.rhizomatis accessions collected from different locations in Sri Lanka. Proceeding of the Fourth Symposium on Plantation Crop Research. 2012; p 17
  11. Rajkumar G, Weerasena OVDSJ, Fernando KKS, Ratnasiri PW. Morphological and Molecular comparison of O.rhizomatis accessions collected from different locations in Sri Lanka. Proceeding of the Fourth Symposium on Plantation Crop Research. 2012; p 17
  12. Kalubowila HV, De Silva JLP, Gunawardena YINS, Manamperi A, Dassanayake RS, Weerasena OVDSJ, Jayathilake MM, Geekiyanage CM. Comparative evaluation of accuracy of two widely used molecular diagnostic methods for JAK2 V617F mutation assessment; As PCR and PCR RFLP.13th Annual Academic session of Sri Lanka College of Hematologists. 2012; p

  13.     2011

  14. Rajkumar G, Weerasena OVDSJ, Fernando KKS, Liyanage ASU and Rangika S. Genetic differentiation of Sri Lankan traditional rice (Oryza sativa) varieties and Wild rice species by AFLP markers. Nordic Journal of Botany. 2011; 29 (2): 238–243. doi: 10.1111/j.1756-1051.2011.00998.x
  15. Samarakoon SR, Thabrew I, Galhena PB, Tennekoon KH. Effects of a standardized preparation of a decoction comprised of Nigella sativa (seeds), Hemidesmus indicus (roots), and Smilax glabra (rhizome) on the expression of p53 and p21 genes in human hepatoma cells (HepG2) and livers of mice with chemically induced hepatocarcinogenesis. Tropical Journal of Pharmaceutical research (In press).
  16. Rajkumar G, Weerasena OVDSJ, Fernando KKS, Liyanage ASU. Assessment of Genetic Diversity among Sri Lankan Rice varieties by AFLP Markers. Plant Genetic Resources: Characterization and Utilization. 2011; 9:224-228. doi:10.1017/S1479262111000256
  17. De Silva S, Tennekoon KH, Karunanayake EH, De Silva W, Amarasinghe I, Angunawela P (in press) Novel sequence variants and common recurrent polymorphisms of BRCA2 in Sri Lankan breast cancer patients and a family with BRCA1 mutations. Experimental and Therapeutic Medicine Published online on: Wednesday, August 17, 2011
  18. Jayanthiny P, Tennekoon KH, Karunanayake EH, Kumarasiri JM, Wijesundera APDeS. Di-nucleotide repeat polymorphisms of the insulin-like growth factor-I (IGF-I) gene and their association with IGF-I, insulin-like growth factor binding protein-1 and birth size in a Sri-Lankan cohort. Neonatology 2011; 100:37-43. Online publication 2010
  19. Thanthrige RL, Weerasena OVDSJ, Pushpakumara DKNG. Selection of Artocarpus heterophyllus Lam. (jackfruit) types/varieties using AFLP markers. Proceedings of the 16th International Forestry and Environmental Symposium. Department of Forestry and Environmental Science, University of Sri Jayawardanapura. 2011; p 44
  20. Thanthrige RL, Weerasena OVDSJ, Pushpakumara DKNG, Senevirathne KGS. Genetic differentiation of some Artocarpus heterophyllus Lam. (jackfruit) varieties in Sri Lanka and development of varietal specific AFLP markers. Proceedings of the 67th Annual Session of Sri Lanka Association for the Advancement of Science. 2011; p 58
  21. Rajkumar G, Weerasena OVDSJ, Silva R. Comparison of Similarity Coefficients for Amplified Fragment Length Polymorphism molecular markers used for Cluster analysis and genetic relationship within Sri Lankan rice varieties. Proceedings of the international statistics conference. 2011; p 58
  22. Siriwardhanar DAS, Samarasekera R, Peiris ML, Weerasena OVDSJ, Weerasinghe IS, Ahangama D. Gene activity relationship of Bacillus thuringiensis Sri Lankan strains against dipteran, lepidopteran and coleopteran pests. Chemistry in Sri Lanka. 2011;28 (2), 13.
  23.     2010

  24. Sugathadasa BHKR, Tennekoon KH, Karunanayake EH, Kumarasiri JM Wijesundere APDeS. Association of -2548 G/A polymorphism in the leptin gene with preeclampsia/ pregnancy induced hypertension. Hypertension in Pregnancy.
    2010; (doi:10.3109/10641950903214617).
  25. Samarakoon SR, Thabrew I, Galhena PB, De Silva D, Tennekoon KH. A comparison of the cytotoxic potential of standardized aqueous and ethanolic extracts of a polyherbal mixture comprised of Nigella sativa (seeds), Hemidesmus indicus (roots) and Smilax glabra (rhizome). Pharmacognosy Res. 2010; 26:335-342.
  26. Sawai H, Otani H, Arisue N, Palacpac N, de O Martins L, Pathirana S, Handunnetti S, Kawai S, Kishino H, Horii T and Tanabe K. Lineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites. BMC Evolutionary Biology.2010; 10: 52.
  27. Wickramarachchi,Premaratne PH, Dias S, Handunnetti SMand Udagama-Randeniya PV. Genetic complexity of Plasmodium vivax infections in Sri Lanka reflected at the Merozoite Surface Protein-3α locus Annals of Tropical Medicine and Parasitology 2010; 104:95-108.
  28. Rajkumar G , Weerasena OVDSJ , Fernando KKS , Liyanage ASU. AFLP Analysis of Genetic Relationships and Diversity of Sri Lankan Oryza sativa cultivars (Improved Varieties). Journal of Biotechnology. 2010; 150S:539. doi:10.1016/j.jbiotech.2010.09.886
  29. Pathirana PPSL, Ekanayake K, Howard RJ, Mendis KN, and Handunnetti SM. Expression of surface antigens, cytoadherence and their association with clinical symptoms in acute Plasmodium falciparum infections from Sri Lanka. The Journal of National Science Foundation. 2010; 38:233-240.
  30. Murugananthan A, Karunanayake EH, Tennekoon KH. Cloning and characterisation of alkali myosin light chain gene (MLC-3) of cattle filarial parasite Setaria digitata. IIAOB Journal. 2010 1; 1-10
  31. Gomes TS, Lindner U, Tennekoon KH, Karandagoda W, Gortner L, Obeid R. Homocysteine in small-for-gestational age and appropriatefor-gestational age preterm neonates from mothers receiving folic acid supplementation Clin Chem Lab Med 2010; 48:1157–1161
  32.     2009

  33. Handunnetti SM, Kumara RR, Nanayakkara AA, Deraniyagala SA, Ratnasooriya WD. Anti-inflammatory activity of methanolic leaf extract of Ixora coccinea. Pharmacognosy Research. 2009; 1:80-90.
  34. Dassanayake PN, Everad JMDT, Karunanayake EH, Nandadasa HG. Analysis of coconut (Cocos nucifera L.) diversity using microsatellite markers with emphasis on management and utilization of genetic resources. Journal of National Science Foundation, Sri Lanka. 2009;37: 99-109.
  35. Dassanayake RS, Rodrigo WWR, Karunanayak EH, Weerasena OVDSJ, Chandrasekharan NV. A putative nuclear growth factor-like globular nematode specific protein. Bioinformation. 2009; 3:370-374
  36. Silva NY, Tennekoon KH, Senanayake L, Karunanayake EH. Cord blood leptin levels in normal pregnancy, pregnancy induced hypertension and gestational diabetes mellitus. Ceylon Medical Journal. 2008; 53:79-82.
  37. De Fonseka WAIRS, Kariyawasam KWJC, Kumara RR, Attanayake DPSTG, De Silva ED, Ratnasooriya WD and Handunnetti SM. In vitro Anti-Inflammatory Activity of Aqueous Leaf Extract of Vitex negundo. Agricultural Research Symposium, Wayabma University. 2008; 8:149-153.
  38. Sangeetha MD, Nanyakkara HLC, Kumara RR, Attanayake DPSTG, De Silva ED, Ratnasooriya WD and Handunnetti SM. Effect of Aqueous Seed Extracts of Caesalpinia bonduc on Nitric Oxide Production by Rat Peritoneal Cells in vitro. Agricultural Research Symposium, Wayamba University 2008; 8:165-170.
  39. Weerakoon SR, Weerasena OVDSJ, Peiris PKD, Somaratne S. Differentiation of Sri Lankan mustard (Brassica juncea) accessions using FALFP markers and Agro-Morphological data. Proceedings of International Society of Biotechnology Conference, Skikim, India, 2008 239-243
  40. Niroshini E, Everad JMDT, Karunanayake EH, Tirimanne TLS. Detection of sequence characterized amplified region (SCAR) markers linked to sex expression of Carica papaya L. Journal of National Science Foundation, Sri Lanka. 2008;36: 145-150.
  41. Munasighe RA, Ileperuma M, Kapilananda GM, Premawansa G, Handunnetti SM, Premawansa S. Spleen modulation of cytoadherence properties of Plasmodium falciparum. Scandinavian Journal of Infectious Diseases. 2008;41:538-539.
  42. Wijayalath W, Cheesman S, Rajakaruna J, Handunnetti S, Carter R, Pathirana S. Evidence for strain-specific protective immunity against blood-stage parasites of Plasmodium cynomolgi in toque monkey. Parasite Immunology. 2008;30: 630-636.
  43. De Silva W, Karunanayake EH, Tennekoon KH, Allen M, Amarasinghe I, Angunawala P, Ziard MH. Novel sequence variants and a high frequency of recurrent polymorphisms in BRCA 1 gene in Sri Lankan breast cancer patients and at risk individuals. BMC Cancer. 2008; 8:214.
  44. Munasinghe-Gunasekera A, Wickramarachchi WTA, Ganguli I, Perera KLRL, Premaratne H, Handunnetti SM, Udagama-Randeniya PV, Wirth DF. Genetic diversity and selection at the Plasmodium vivax Apical Membrane Antigen-1 (PvAMA-1) locus in a Sri Lankan Population. Molecular Biology and Evolution. 2007; 24: 939-942.
  45. Tanabe K, Escalante A, Sakihama N, Honda M, Arisue N, Horii T, Culleton R, Hayakawa T, Hashimoto T, Longacre S, Pathirana S, Handunetti S, Kishino S. Evolution of msp1 polymorphism after speciation of Plasmodium vivax and Plasmodium cynomolgi, a P. vivax-related macaque malaria parasite. Molecular and Biochemical Parasitology. 2007;156: 74-79.
  46. Pathmaperuma AN, Tennekoon KH, Senanayake L, Karunanayake EH. Maternal and cord blood levels of insulin-like growth factors –I and -II and insulin-like growth factor binding protein-1: correlation with neonatal and maternal anthropometric indices. Ceylon Medical Journal. 2007; 52: 48-52.
  47. Tennekoon KH, Pathmaperuma AN, Senanayake L, Karunanayake EH. Insulin-like growth factors -I and -II and Insulin-like growth factor binding protein-1 during normal pregnancy in women: correlation with other placental hormones. Ceylon Medical Journal. 2007; 52: 8-13
  48. Tennekoon KH, Eswaramohan, T, Karunanayake EH. Effect of leptin on prolactin and insulin-like growth factor-I secretion by cultured rat endometrial stromal cells. Fertility and Sterility. 2007; 88: 193-199
  49. Wickramarachchi WTA, Illeperuma RJ, Perera KLRL, Longacre S, Handunnetti SM, Udagama-Randeniya R. Subclass specific antibody response to recombinant antigens representing Plasmodium vivax Merozoite Surface Protein -1, p19 and p 42 in endemic and non-endemic populations of Sri Lanka. International Journal of Parasitology. 2007;37:199-208.
  50. Ariyaratne HACK, Everad JMDT, Karunanayake EH. Diseased sugarcane in Sri Lanka is infected with sugarcane grassy shoot and /or sugarcane white leaf phytoplasma. Australasian Plant Diseases Notes. 2007; 2: 123-125.
  51. Wickramarachchi T, Premaratne PH, Perera KLRL, Bandara S, Kocken CHM, Thomas AW, Handunnetti SM and Udagama-Randeniya PV. Natural human antibody responses to Plasmodium vivax Apical Membrane Antigen 1 under low transmission and unstable malaria conditions in Sri Lanka. Infection & Immunity. 2006; 74:798-801.
  52. Merino EF, Fernandez-Becerra C, Alan C, Durham M, Ferreira JE, Tumilsci VF, d’Arc-Neves J, da Silva-Nunes M, Ferreira MU, Wickramarachchi TA, Udagama-Randeniya PV, Handunnetti SM and del Portillo HA. Multi-character population study of the vir subtelomeric multigene superfamily of Plasmodium vivax, a major human malaria parasite. Molecular Biochemical Parasitology. 2006; 149: 10-16.
  53. Mewan KM, Liyanage AC, Everad JMDT, Gunasekera MTK, Karunanayake EH. Studying genetic relationship among tea (Camelina sinensis) cultivars in Sri Lanka. S.L.J. Tea Sci. 2005; 70, 42-53.
  54. Pathirana SL, Alles HA, Sumith Bandara, Myat Phone-Kyaw, Perera MK, Wickremesinghe AR, Mendis KN and Handunnetti SM. ABO blood group types and protection against severe disease in Plasmodium falciparum infections. Annals of Tropical Medicine & Parasitology. 2005; 99: 119-124.
  55. Tennekoon K H, Wasalathanthri S, Jeevathayaparan S, Karunanayake E H. Serum leptin and lactational amenorrhoea in well-nourished and undernourished lactating women. Fertility and Sterility. 2005;83: 988-994
  56. Weerasena OVDSJ, Chandrasekharan NV, Wijesundera RLC, Karunanayake EH. Development of a DNA probe and a PCR based diagnostic assay for Rhizoctonia solani using a repetitive DNA sequence cloned from a Sri Lankan isolate. Mycological Research. 2004;108: 649-653
  57. Weerasena OVDSJ, Steffanson BJ, Falk AB. Conversion of an amplified fragment length polymorphism marker into a co-dominant marker in the mapping of the Rph 15 gene conferring resistance to barley leaf rust, Puccinic hordeu Otth. Theoretical and Applied Genetics. 2004;108: 712-719.