MSc Dissertations IBMBB – 2005 to 2009 Intakes

Guidelines for MSc Dissertations

Name of the Student

Gender

Year of entry

Studies
Completed

Degree
Programme

Title of the Dissertation

S S P De Silva

M

2005

2006

MSc/CMI

Studies on anti-inflammatory effects of aqueous extracts of Vitex negundo, Ixora coccinea and Alpina calcarata on rat peritoneal cells

M U Dissanayake

F

2005

2006

MSc/CMI

Immunoepidemiology of the Plasmodium vivax merozoite surface protein-4 (MSP-4) in Sri Lanka. A preliminary study

A D Gunaratne

F

2005

2006

MSc /MLS

Analysis of germ line mutations in selected exons of the TP53 gene in breast cancer patients

A D N Dalpethado

M

2005

2007

MSc/MLS

Amplification and sequence characterization of resistance gene analog markers from Sri Lankan traditional rice varieties

K Kumaraguru

F

2005

2007

MSc/CMI

Anti-inflammatory activity of the aqueous and methanol rhizome extracts of Alpina calcarata

H A C K Rodrigo

F

2005

2007

MSc / MLS

Screening of a selected group of Sri Lankan breast cancer patients for germ-line mutations in exon 7 of BRCA 2 gene

H V G S Wickramaratne

F

2005

2007

MSc/MLS

Screening for germ line mutations in exon 12 of BRCA 2 gene in a selected group of patients with family history of breast cancer and ovarian cancer

S D Gnanaratnam

F

2005

2008

MSc/CMI

A study of maternal IGF-I levels in pregnancy induced hypertension

K G S U  Ariyawansa

M

2006

2007

MSc /MLS

Isolation and characterization of putative plant disease resistance gene analogs (RGA) from Sri Lankan traditional rice varieties

S Goonetilleke

F

2006

2007

MSc/CMI

Determination of serum IgA and rheumatoid factor IgA-RF in association with clinical manifestations in a population of rheumatoid arthritis patients in Sri Lanka

W L Indika

M

2006

2008

MSc /MLS

Gln223Arg polymorphism in the leptin receptor gene in pregnancy induced hypertension

A A Nanayakkara

M

2006

2007

MSc/CMI

Anti-inflammatory effects of the methanolic leaf extracts and semi-purified fractions of Ixora coccinea on human leucocytes

R A C R Ranasinghe

F

2006

2007

MSc /MLS

Optimisation of PCR conditions for the amplification of
hypervariable region I and hypervariable region II in the human mitochondrial D loop      

J G Rozani

M

2006

2007

MSc /MLS

Screening for germ-line mutations of exon-8 in the P53 gene in a family with a BRCA-1 mutation

M Senanayake

M

2006

2007

MSc /MLS

Genetic differentiation of finger millet varieties using AFLP markers

R D W M A S A Wijekoon

M

2006

2007

MSc /MLS

Development of a simple sequence repeat DNA polymorphism (SSR) marker to detect salinity tolerant rice varieties in Sri Lanka

R Withatchchi

M

2006

2008

MSc/CMI

Detection of micro metastasis of breast cancer by immunohistochemical identification of K-19 antigen in axillary lymph nodes

KWJC Kariyawasam

F

2007

2008

MSc/CMI

In vitro anti inflammatory mechanisms of Vitex negundo

HLC Nanayakkara

F

2007

2008

MSc /CMI

Effects of aqueous extracts of Anisomeles indica, Caesalpinia bonduc and Toddalia asiatica on pro-inflammatory mediators involved in the pathogenesis of malaria

M E Perera

F

2007

2008

MSc /MLS

Development of a molecular marker to detect salt tolerant Sri Lankan Rice varieties

SSR Samarakoon

M

2007

2008

MSc/MLS

Cloning, sequencing and characterization of filarial parasite specific genes

A Sivapatham

F

2007

2008

MSc/CMI

Feasibility of using blood collected on to filter paper for assessing hormone levels by enzyme-linked immunosorbent assay

M S Somaratna

F

2007

2008

MSc /CMI

Detection of human antibody responses against domain II of Plasmodium vivax apical membrane antigen-1 using synthetic peptides in Sri Lanka

K Vythilingam

F

2007

2008

MSc /MLS

Characterization of mutations and sequence variants in exon 11 of BRCA -1 gene in Sporadic Breast Cancer: A preliminary study on Sri Lankan patients

Y C Aluwihare

F

2008

2009

MSc/MLS

Development of PCR primers from putative disease resistant gene identified from rice variety “Rathuheenti and identification of disease resistant gene analogs from Sri Lankan rice varieties

ADDS Amarasekara

F

2008

2009

MSc /CMI

Laboratory tests to establish markers of sperm oxidative stress in Sri Lankan males

RI Gunaratne

F

2008

2009

MSc/CMI

Predictive value of nitric oxide levels on disease severity and outcome of leptospirosis in Sri Lankan patients

Madhusahni Kannanagara

F

2008

2009

MSc/MLS

Genetic diversity assessment of Finger millet using microsatellite markers

KLNS Perera

M

2008

2009

MSc /MLS

Molecular characterization of Mycobacterium tuberculosis isolates in Sri Lanka utilizing the mycobacterium interspersed repetitive (MIRU) typing method

SIC  Silva

F

2008

2011

MSc/MLS

Differentiation of Selected Piper nigrum L (Black Pepper) cultivars in Sri Lanka using morphological and AFLP markers

S Sinnathamby

F

2008

2009

MSc /MLS

H 19 polymorphism in newborns born to mothers with pregnancy induced hypertension/pre-ecalmpsia

T Siriwardena

F

2007

2009

MSc/MLS

IGF-II Apa 1 polymorphism in newborns born to mothers with pregnancy induced hypertension/pre-ecalmpsia

D P Yasasni

F

2008

2010

MSc/MLS

The CA dinucleotide repeat polymorphism of the promoter of the IGF-I gene in preeclampsia / pregnancy indiced hypertension

Y D De Silva

F

2008

2010

MSc/MLS

Detection of micrometastasis of breast cancer using Cytokeratin-19 based RT-PCR

RML Tanthirige

F

2008

2011

MSc/MLS

Development of specific AFLP markers for identification of jak fruit (Artocarpus heterophyllus Lam) varieties in Sri Lanka

NKRD Wickramasinghe

F

2008

2009

MSc /CMI

Modulation of human neutrophil functions by leaf extracts of Ixora coccinea

K Kumarasivam

F

2009

2010

MSc/MLS

Restriction fragment length polymorphism of the OSA3 gene in Oriza sativa

ARMMNK Ratnayake

F

2009

2010

MSc/MLS

Optimisation of PCR conditions for detection of survivin gene expression in hepatocellular carcinoma cell line

SS Wickramasekara

F

2009

2010

MSc/MLS

Molecular analysis of the F1 hybrid plants (triploids ABC) to confirm the true bybridity between Brassica juncea and B. oleracea

AS Gammulle

F

2009

2010

MSc/CMI

Effect of concentrated Carica papaya leaf extract on rat platelet count

TL Kalugalage

F

2009

2010

MSc/CMI

Studies on serum NOx levels in Sri Lankan patients with leptospirosis

PDNN  Sirisena

F

2009

2010

MSc/CMI

Effect of aqueous leaf extract of Vitex negundo on human phagocytic cells

R Tippalagama

F

2009

2011
(to be submitted shortly)

MSc/CMI

HLA typing MHC class I molecules by PCR and sequencing in Sri Lanka

AMDSD De Silva

F

2009

2011

MSc/CMI

Studies on the effect of aqueous leaf extracts of Ixora coccinea and Vitex negundo on neutrophil chemotaxis

T Wickramasinghe

F

2009

In progress

MSc/CMI

Studies on humoral response to two strains of Plasmodium cynomolgi using cynomolgi toque monkey system

MSc Dissertations – Indirect students (those registered at other HEIs who carried out research projects at the IBMBB)

Name of the Student

Gender

Year of entry

Studies Completed

Degree Programme

Title of the Dissertation

BDSL De Tissera

F

2003

2005

MSc, PGIS, UoP

Characterization of germline mutations in the breast cancer gene 1 exon 15

WAGD Indragupta

M

2005

2006

MSc, Faculty of Medicine, Colombo

Differentiation of traditional Sri Lankan  rice varieties using AFLP markers

Saluja Thambirajah

F

2005

2006 (Dissertation completed in 2006; course examination completed in 2010)

MSc, Faculty of Medicine, Colombo

Cloning and characterization of S. digitata specific protein encoding genes

Jayanthini Poopalapillai

F

2005

2006

MSc, Faculty of Medicine, Colombo

A study on maternal and cord blood IGF I, IGF II and IGFBP-1 levels in normal and complicated pregnancies

Inoka Sandanayake

F

2005

Lab work completed, Dissertation not written up

MSc, PGIS, UoP

Polymorphism in selected Exons of the Leptin receptor in relation to lactational amenorrhoea

YS Wijayasinghe

M

2007

2008

MSc. Faculty of Science, Colombo

Maternal plasma levels of placental growth factor in pregnancy induced hypertension/pre-eclampsia

MLS: Molecular Life Sciences/IBMBB; CMI: Cellular and Molecular Immunology/IBMBB, PGIS: Postgraduate Institute of Science, UoP: University of Peradeniya